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A man was shot and killed early Saturday in south St. Louis City.
More changes are coming to the St. Louis Post-Dispatch.
A conservative non-profit is asking the DOJ to look into Washington University’s medical school.
When porch pirates were caught on video stealing packages from a porch in Belleville recently, the victims were startled by what they saw
St. Louis police are investigating after a woman’s body was found Friday in a vacant North City lot.
A south St. Louis County five-year-old is bringing dinosaur enthusiasts together from across St. Louis
With cold, flu and RSV season starting, Missouri hospitals are gearing up for more patients
If you’ve been anywhere today, or on the internet, it’s hard not to hear someone talking about Taylor Swift
St. Louis County announced a change to its policy Friday that looks to crack down on drunk and impaired driving
The Barnes and Noble in Ladue was boarded up Friday evening after a vehicle crashed into the building
10 Day Forecast
For the next few days, a handful of goats are penned up in the park’s bird sanctuary area, where honeysuckle and other invasive plants had taken over
Imported branded and patented pharmaceuticals are now facing a 100% tariff tax. That could be passed down to small local pharmacies or patients, but some companies are already negotiating their way out
The pieces are coming together for Rawlings giant glove.
Terrico Kingpin lives in the city and said the former JJ’s nightclub at Vandeventer and Market is yet another eyesore in the city
Local groups continue to come together to make sure those impacted by the May 16 tornado aren’t forgotten.
‘Telemundo St. Louis’ will host its second annual health fair on Saturday
Members of the St. Louis City Board of Aldermen called on the city to commit to diversity in awarding city contracts
A man has been arrested in connection with two separate assaults of cyclists over the summer.
A St. Louis man has been accused of shooting a woman in her 80s during a road rage incident, and then telling police he had a pipe bomb.
An individual who was injured in north St. Louis County explosion has hired a national law firm Friday.
The Missouri State Highway Patrol is investigating after a man was struck and killed in Jefferson County on Friday morning.
Police are investigating after a man was shot and killed overnight in Dutchtown.
USA Today’s best fall festival in the country starts next week. It’s in Indiana, but holds surprising ties to St. Louis.
The Board of Aldermen of St. Louis is expected to discuss and vote on the final passage and support for developing thoughtful frameworks for data centers in St. Louis.
Cori Bush has announced she is running for U.S. Congress.
The life of a St. Louis symbol of hope is now on the big screen as the first major motion picture filmed in St. Louis since the return of film tax credits.
The University of Missouri—St. Louis told First Alert 4 it is laying off 40 members of its faculty staff
As the federal government shutdown drags on, Veterans Affairs nurses in St. Louis say they are still showing up for work — even if their paychecks may be delayed.
The Zootoberfest kicks off at the Saint Louis Zoo Saturday.
Members of the American Federation of Government Employees (AFGE) Local 2192 held a rally in the Metro East in support of federal government workers and to call for an end to the government shutdown
St. Charles Community College celebrated the opening of a brand new center on Thursday to help students enter trade fields
Workers with the St. Louis County transportation department began a repaving project in the 4,000 block of Weber Road last week. But the workers only paved one side of the street
Police departments across the metro area in Missouri now qualify for new state funding
Health officials have released new data on the health risks metro residents face if living near radioactive waste in Coldwater Creek, left over from atomic bomb production decades ago
Clergy group gets $1 million from Missouri for tornado relief, aiming to get it out ‘as fast we can’
St. Louis storm victims got a boost Thursday as a group of clergy announced $1 million in state money going to storm relief.
A man from Edwardsville is accused of distributing child pornography.
General Mills announced it is closing a pizza crust manufacturing facility in St. Charles
The NHL season is almost here and the St. Louis Blues get their season started next Thursday night against the Minnesota Wild
Watch as First Alert 4’s Steve Harris shows how one man’s generosity is making a difference
Interstate 70 has reopened at Adelaide Avenue after a pedestrian was struck and killed Thursday morning.
St. Louis native Nikki Glaser announced today that she is coming to the Lou for her next comedy show.
U.S. Sen. Bernie Sanders called for Boeing to work with IAM Union members to end the months-long strike in St. Louis.
The 2025 Bands of America competition is coming back to St. Louis on Friday, October 17 at The America’s Center.
A woman is in critical condition after being shot in north St. Louis City on Wednesday.
Illinois State Police Officials reported on Thursday that the suspect involved in the shooting in New Canton was found dead in his home.
Both Missouri and Illinois implemented new COVID-19 guidelines for the fall, some of which differ from the Federal guidelines.
Two people were sent to the hospital overnight after a car crashed into a house in west St. Louis.
The city continues to work on drafting regulations on the matter that has become a nationwide discussion.
Signs went up as part of the Urban League's Slow Down campaign following several accidents along a mile stretch of West Florissant.